Abstract：Gene editing technology is a precise modification technique that can manipulate DNA sequences in living organisms. In order to understand the global development trends in this field, particularly with regard to agricultural animal gene editing, the present study utilized the bibliometric methods to analyze research data from 2015 to 2022 in the field of gene editing technology. In this study, we systematically examined the main research institutions, teams, research frontiers, and current status of agricultural animal gene editing technology research. The results showed that China is in a leading position internationally in gene editing technology research at the literature level, as it is ranked second in the world in terms of the number of gene editing technology-related papers published between 2015 and 2022. Eight of the top 20 institutions being in China, accounting for 40% of the total in the world. However, compared with developed countries, such as the United States, China still lags behind in terms of core technology innovation, gene editing system development, optimization and Cas protein discoveries, all of which are mainly being conducted overseas. Although China ranks second in the world in terms of the number of papers published in top international academic journals, however, it is far behind the United States. In the Nature Biotechnology, China accounts for only one-fifth of the total number of papers, with 31 papers published. The number of research reports on gene editing technology in agricultural animals is relatively small, but it is increasing year by year. The application of gene editing technology in animal breeding has immense potential in the field of agricultural animal breeding, particularly in developing disease-resistant breeds. Finally, we look forward to the prospect of gene editing technology and the development trends of agricultural animal breeding field based on the current situation and national conditions, in order to provide us with a reference for using gene editing technology to solve major problems in agricultural animal breeding, especially disease resistance breeding.
张萌萌, 蒋颖, 李宁. 全球农业动物基因编辑基础研究发展动态分析[J]. 农业生物技术学报, 2024, 32(1): 220-233.
ZHANG Meng-Meng, JIANG Ying, LI Ning. Analysis of the Development Trends in Global Agricultural Animal Gene Editing Fundamental Research. 农业生物技术学报, 2024, 32(1): 220-233.
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