The Effects of Dietary Energy Levels on Ovarian and Uterine Expression of Insulin-like Growth Factor-I Receptor and Epidermal Growth Factor Receptor mRNA in Prepubertal Gilts
Bo LI He ZHANG Jin ZHANG Bo-xing SUN Lu CHEN Yan-ling SUN Xu ZHOU
Abstract：Nine prepubertal gilts (JunMu No.1) were randomly allocated to three groups (n=3) and fed with a high level digestive energy (Group H), a low level digestive energy (Group L), and a control group digestive energy (Group M) diet, respectively, for 14d. Free access of water was provided throughout the whole research period. Ovaries and uteruses were collected, after 2 weeks energy treatment, and processed for determination of the absolute quantities of IGF-IR and EGFR mRNA by using real-time PCR. The ovaries and uteruses in the Group H expressed significantly greater amount of IGF-IR and EGFR mRNA than in the Group M and Group L (p＜0.05). But only the ovaries in the Group L expressed significantly less amount of IGF-IR and EGFR mRNA(p＜0.05) than in the Group M. The present study demonstrated that high energy intake markedly enhances the ovarian and uterine expression of IGF-IR and EGFR in prepubertal gilts, whereas, insufficient energy intake markedly inhibits such expressions. The result suggests that IGF-IR and EGFR might be involved in mediating the effects of energy intake on the development of reproductive system in prepubertal gilts.
收稿日期: 2007-07-16
通讯作者:
周虚
引用本文:
李波 张贺 张晶 孙博兴 陈璐 孙艳玲 周虚. 能量对初情期前母猪卵巢和子宫IGF-1R和EGFR mRNA表达的影响[J]. , 2008, 16(2): 0-.
Bo LI He ZHANG Jin ZHANG Bo-xing SUN Lu CHEN Yan-ling SUN Xu ZHOU. The Effects of Dietary Energy Levels on Ovarian and Uterine Expression of Insulin-like Growth Factor-I Receptor and Epidermal Growth Factor Receptor mRNA in Prepubertal Gilts. , 2008, 16(2): 0-.
