Abstract：Cow (Bos taurus) mastitis is an inflammatory disease caused by pathogenic microorganism infection,trauma or other factors in mammary gland tissue. It has complex causes,high incidence and expensive treatment cost,which seriously restricts the development of dairy industry. MicroRNA (miRNA) can regulate the expression of messenger RNA (mRNA) at the post-transcriptional level,thus regulating biological processes including body immunity. In recent years,it has been found that miRNA played an important role in the occurrence and development of mastitis in dairy cows. In this paper,the expression pattern and molecular regulation mechanism of miRNA in mammary tissue,peripheral blood,milk of different types of mastitis cows and pathogenic bacteria-induced mammary epithelial cells were reviewed,and the problems that need to be solved were analyzed and prospected,which will provide reference for researchers to further understand the related fields.
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