转录组学在病原菌所致牛羊乳房炎中的应用研究进展

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摘要乳房炎主要是由病原微生物感染引起的乳腺炎症反应，是哺乳动物，尤其是牛、羊等动物易发的疾病之一，一直以来成为相关领域科研工作者广泛关注的对象。由于乳房炎的致病机理十分复杂，在受到传统方法不能根治该病的困扰之际，转录组在内的组学技术的兴起为乳房炎发生过程中病原微生物的致病机制及宿主的抗病机制研究提供了很好的技术平台和研究思路。本文综述了转录组学在牛羊乳房炎中的国内外最新研究进展，为深入探究宿主应对病原菌感染的分子防御机制及乳房炎的诊断与预后提供参考。

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	李讨讨
	赵兴绪
	马友记

关键词 ：牛, 羊, 乳房炎, 转录组学, 免疫应答

Abstract：The mastitis is one of the most common diseases mainly caused by pathogenic microorganisms for female mammals, especially in cattle and sheep, and also has long been focused highly by researchers in the field concerned. Under the background that mastitis cannot be effectively treated with conventional approaches, the rising of omics technologies including transcriptomics provide good technology platforms and research ideas for investigating pathogenic mechanism of pathogens and resistant mechanism of host during mastitis. In this paper, the recent progresses in research on the application of transcriptomics in cattle and sheep mastitis were reviewed. This review offers references for the in-depth study of molecular mechanisms of host defense against bacterial infections and diagnosis and prognosis of mastitis.

Key words： Cattle Sheep Mastitis Transcriptomics Immune response

收稿日期: 2019-03-07 出版日期: 2019-07-22

ZTFLH:

S858.2

基金资助:国家重点研发计划课题;甘肃农业大学优秀博士学位论文培育项目;甘肃省现代草食畜产业技术体系项目

通讯作者: 马友记

引用本文:

李讨讨赵兴绪马友记. 转录组学在病原菌所致牛羊乳房炎中的应用研究进展[J]. , , (): 0-0.

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http://journal05.magtech.org.cn/Jwk_ny/CN/ 或 http://journal05.magtech.org.cn/Jwk_ny/CN/Y/V/I/0

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