Research Advances on Transcriptomics in Cattle and Sheep Mastitis Caused by Pathogenic Bacteria
LI Tao-Tao1, 2, ZHAO Xing-Xu3, MA You-Ji1, 2, *
1 College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China; 2 Gansu Engineering Laboratory of Sheep Breeding Biotechnology, Minqin 733300, China; 3 College of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China
Abstract：The mastitis is one of the most common diseases mainly caused by pathogenic microorganisms for female mammals, especially in cattle and sheep, and also has long been focused highly by researchers in the field concerned. Under the background that mastitis cannot be effectively treated with conventional approaches because of its complexity in the pathogenesis, the rising of omics technologies including transcriptomics provide good technology platforms and research ideas for investigating pathogenic mechanism of pathogens and resistant mechanism of host during mastitis. In this paper, the recent progresses in research on the application of transcriptomics in cattle and sheep mastitis were reviewed. This review offers references for the in-depth study of molecular mechanisms of host defense against bacterial infections and diagnosis and prognosis of mastitis.
李讨讨, 赵兴绪, 马友记. 转录组学在病原菌所致牛羊乳房炎中的研究进展[J]. 农业生物技术学报, 2019, 27(9): 1681-1691.
LI Tao-Tao, ZHAO Xing-Xu, MA You-Ji. Research Advances on Transcriptomics in Cattle and Sheep Mastitis Caused by Pathogenic Bacteria. 农业生物技术学报, 2019, 27(9): 1681-1691.
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