Association of Polymorphism C1149G of Nuclear Enriched Abundant Transcript1 Gene(NEAT1) with Hematological and Immune Traits in Landrace Pig(Sus scrofa)
Abstract：Nuclear enriched abundant transcript 1(NEAT1) is a long non-coding RNA that is involved in immune response, paraspeckle formation and mRNA export. In this study, a single nucleotide polymorphism C1149G in porcine(Sus scrofa) NEAT1 was detected by PCR-RFLP. Allele frequencies varied greatly among different pig breeds examined, and the association results indicated that piglets with the genotype CC had significantly higher levels of Classical swine fever virus (CSFV) antibody (0 and 17 days), mean corpuscular volume(0 days) and mean corpuscular hemoglobin content (32 days), but lower platelet distribution width (32 days), mean platelet volume (32 days) and platelet larger cell ratio (32 days) than those with genotype GG or CG in a Landrace population. The results can be provided as references to molecular markers assisted breeding for pigs
