Abstract：Wool fiber is one of the important economic products of sheep. The development of the wool market has stimulated people's demand for different characteristics of wool. Peratin-associated proteins (KAPs)genes--KRTAPs and keratin-associated proteins (KIFs) genes and their respective variant genes are candidate genes for identifying the genetic basis of wool fiber differences. Using the homologous genes of human or goat and other mammalian keratins, we can identify the sheep genome and explore new potential functional KRTAPs or KIFs genes. In this review, the morphological structure of hair follicles is introduced, and the development of keratin-related protein genes is reviewed. The expression and location of KAP protein in hair follicles are also described. Finally, the effect of KRTAPs gene polymorphism on wool traits is summarized. This review provides a theoretical basis for the molecular breeding of sheep hair follicle growth and development and hair fiber traits.
和东迁, 陶金忠, 陈丽尧, 王俊奎. 与毛纤维性状相关的角蛋白相关蛋白研究进展[J]. 农业生物技术学报, 2021, 29(6): 1198-1205.
HE Dong-Qian, TAO Jin-Zhong, CHEN Li-Yao, WANG Jun-Kui. Research Progress of Keratin-related Proteins Related to Hair Fiber Traits. 农业生物技术学报, 2021, 29(6): 1198-1205.
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