Application and Prospect of Functional Microorganisms Based on Synthetic Biology in Comprehensive Treatment of Heavy Metal Pollution
SU Dong-Hai1, GUO Ming-Zhang2, LIU Yang-Er2, ZHOU Zi-Qi2, ZHANG Xiao-Hui1, ZHAI Bai-Qiang, XU Wen-Tao2,*
1 Beijing Polytechnic, Beijing 100029, China; 2 Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100194, China; 3 Zhengzhou University of Light Industry, Zhengzhou 450001, China; 4 Henan Railway Food Safety Management Engineering Technology Research Center, Zhengzhou 451460, China
Abstract：With the development of industry, the content of heavy metals in the earth-surface is increasing, which seriously threatens human health. Among the technologies for treatment of heavy metal pollution, microbial remediation technology has attracted much attention due to its advantages of low cost, simple operation and environmental friendliness. However, the low efficiency of microbial remediation technology limits its application. Synthetic biology combines biotechnology and engineering theory. Through the de novo design of microbial gene network, microorganisms can complete various tasks of artificial design. Synthetic biology has many applications in improving the efficiency of microbial remediation of heavy metals. Under the guidance of synthetic biology, a large number of microbial biosensors for heavy metal detection, microbial functional strains for heavy metal adsorption, and microbial factories for the production of heavy metal nano-particles have been developed. This review provides a new systemic and complete solution for the comprehensive treatment of heavy metals.
苏东海, 郭明璋, 刘洋儿, 周子琦, 张晓辉, 翟百强, 苏东民, 许文涛. 基于合成生物学的功能微生物在重金属污染治理中的应用与展望[J]. 农业生物技术学报, 2021, 29(3): 579-590.
SU Dong-Hai, GUO Ming-Zhang, LIU Yang-Er, ZHOU Zi-Qi, ZHANG Xiao-Hui, ZHAI Bai-Qiang, XU Wen-Tao. Application and Prospect of Functional Microorganisms Based on Synthetic Biology in Comprehensive Treatment of Heavy Metal Pollution. 农业生物技术学报, 2021, 29(3): 579-590.
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