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2025年8月12日 星期二
农业生物技术学报  2020, Vol. 28 Issue (2): 325-332    DOI: 10.3969/j.issn.1674-7968.2020.02.014
  研究评述与展望 本期目录 | 过刊浏览 | 高级检索 |
猪脂肪细胞分化及调控研究进展
巩建飞1,2, 刘欣1*, 孙金海2, 王立贤1*
1 中国农业科学院 北京畜牧兽医研究所,北京 100193 ;
2 青岛农业大学 动物科技学院,青岛 266109
Advances in the Differentiation and Regulation of Porcine (Sus scrofa) Adipocytes
GONG Jian-Fei1,2, LIU Xin1*, SUN Jin-Hai2, WANG Li-Xian1*
1 Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
2 College of Animal Science, Qingdao Agricultural University, Qingdao 266109, China
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摘要 脂肪积累与猪(Sus scrofa)的生长速度和猪肉品质密切相关。脂肪组织的发育依赖于脂肪细胞数量增加和体积增大,在两者相互协调、相互作用下导致脂肪的生成、积累。脂肪细胞分化受精密调控的转录级联控制,转录因子以一种连续的方式激活或抑制彼此的表达。本文综述了猪脂肪细胞分化的过程、脂肪细胞的研究模型、前脂肪细胞诱导分化的方法、脂肪细胞分化的标志因子以及相关的几个重要转录因子的研究现状,旨在为研究猪脂肪细胞分化及脂质代谢机制提供参考。
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巩建飞
刘欣
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王立贤
关键词 脂肪细胞分化调控转录因子    
Abstract:Fat tissue accumulation is closely related to growth efficiency and meat quality in pigs (Sus scrofa). The development of adipose tissue depends on the increasing of adipocytic numbers and size, which leads to the adipogenesis through coordination and interaction. Adipocyte differentiation is controlled by a precisely regulated transcriptional cascade that activates or inhibits each other's expression in a continuous manner. The process of porcine adipocyte differentiation, the research model of adipocytes, the method of preadipocytes differentiation, the marker factors of adipocyte differentiation, and the research progress of several important transcription factors related to porcine adipocyte differentiation were reviewed in this paper, which aims to provide the reference for studying the mechanism of differentiation of pig adipocytes and lipid metabolism.
Key wordsPig    Adipocyte    Differentiation    Regulation    Transcription factor
收稿日期: 2019-07-19     
ZTFLH:  S828  
基金资助:北京市自然基金青年基金项目(6174047)和中国农业科学院科技创新工程(ASTIIP-IAS02)
通讯作者: *firstliuxin@163.com; iaswlx@263.net   
引用本文:   
巩建飞, 刘欣, 孙金海, 王立贤. 猪脂肪细胞分化及调控研究进展[J]. 农业生物技术学报, 2020, 28(2): 325-332.
GONG Jian-Fei, LIU Xin, SUN Jin-Hai, WANG Li-Xian. Advances in the Differentiation and Regulation of Porcine (Sus scrofa) Adipocytes. 农业生物技术学报, 2020, 28(2): 325-332.
链接本文:  
http://journal05.magtech.org.cn/Jwk_ny/CN/10.3969/j.issn.1674-7968.2020.02.014     或     http://journal05.magtech.org.cn/Jwk_ny/CN/Y2020/V28/I2/325
 
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