Fungal Laccase: Multi-biofunction and Complicated Natural Substrates
LIU Ning1*, JIA Hui1*, SHEN Shen1*, CAO Zhi-Yan1,2,3*, DONG Jin-Gao1,2,3*
1 College of Life Sciences, Hebei Agricultural University, Baoding 071001, China; 2 College of Plant Protection, Hebei Agricultural University, Baoding 071001, China; 3 Hebei Key Laboratory of Physiological and Molecular Plant Pathology, Baoding 071001, China
Abstract：Laccase is a polyphenol oxidase containing copper ions, which occur widely in fungi, plants, bacteria and insects. In fungi, laccases are generally in the form of gene families encoding isozymes which are involved in many important biological processes including fungal morphogenesis, pigment synthesis, infection and pathogenesis. Laccase catalyze the oxidation of a wide variety of substrates such as polyphenols, aromatic amines and lignin. However, the research about laccases mainly focuses on the degradation and decolorization of artificial compounds such as toxic compounds. There are few studies on the identification and analysis of natural catalytic substrates and their metabolic pathways in fungi. In this paper, the biological functions of fungal laccase and its natural catalytic substrate are reviewed to clarify the mechanism of laccase biological function.
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