Abstract：Pleiotropic drug resistance (PDR) is an important subfamily member of the ABC transporter superfamily, which plays important role in response to stress, plant growth and development, but little research has been done in wheat (Triticum aestivum). In order to investigate the response of wheat PDR gene family to stress, genome-wide identification and bioinformatics analysis of TaPDR gene family were performed in this study, and the responses to abiotic stress were verified by qPCR. The results showed that 76 TaPDR genes were mainly distributed on chromosome 3, 5 and 7. The number of coding amino acids was 1 242~1 517, and the molecular weight was 140.69~170.99 kD, pI was between 6.22 and 8.94. According to phylogenetic analysis, TaPDR genes were divided into 5 groups (Class Ⅰ~Ⅴ), most of TaPDRs had highly conserved protein motifs, and TaPDR genes in the same group had more similar gene structure. 10 pairs of tandem repeat genes and 56 pairs of segmental duplication genes were founded with gene duplication analysis method. The tissue-specific analysis showed that TaPDR genes exhibited different expression levels in different tissues. Most TaPDR genes were highly expressed in roots. qPCR results showed that TaPDR genes could respond to salt, drought, cadmium and abscisic acid treatment in different degree. The results provide a reference basis for the mechanism of TaPDR gene family in abiotic stress response.
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