Abstract:The proportion of transgenic crop plant area in developing countries increased year by year, and exceeded developed countries for the first time since 2012. Brazil developed from forbidding planting transgenic soybeans to the country whose transgenic crop plant area is the second largest over the global. China can learn some management patterns from Brazil. This paper elaborated on the development of genetically modified organisms in Brazil and China, and compared genetically modified organisms safety management from the laws and regulations, management systems and identification. China can improve the management of genetically modified organisms from the following aspects: Formulating laws and regulations to keep pace with the times according to the development of genetically modified technology and genetically modified organisms; perfect the management system; increasing government information transparency, with timely and widely propaganda; strengthening law enforcement; adopting a more scientific way of identification. In order to promote the sustainable development of genetically modified technology in our country, China must take effective measures to establish and strictly execute a supervision system, strengthen the safety management of genetically modified organisms and their products, and solve the problems of genetically modified food safety, further speeding up commercialisation of genetically modified crops in China.