Abstract:The transgenetic modified organism(GMO) has developed rapidly since it is born. As the commercialization of GMOs is growing more and more fast, the food safety and the environmental safety of GMOs have been paying more attention by the government and the public. For the supervision of the GMOs, many countries have been taken the identification laws in different manners, to supervise the food and feed which contain the GMO content for protecting the right to know for the consumers. In this assay, we introduce the different kind of GMOs identification laws that are taken in different countries. By contrasting with Chinese laws, we have achieved the drawbacks of the laws in China, providing the theoretical basis to improve. We introduced the detection method based on nuclear acid and protein, also, for the latest detection method, such as next-generation sequencing, digital-PCR, loop-mediated isotheral amplification, we concluded the research progress of these techniques and predicted the future in GMO detection area. Finally, we predicted the future, challenge and develop direction of GMO detection.