Abstract：Bcl-2 associated athanogene (BAG) family proteins possess different biological functions, and widely participate in multiple biological processes such as tumor regulation, apoptosis and stress response. Currently, the researches of BAG family in plant mainly focus on Arabidopsis thaliana. In this review, we summarized the biological functions of BAG family in plant: (1) C terminal of BAG protein contains an evolutionarily conserved BAG domain, which can interact with Hsp70 related proteins. (2) Specific domains of N terminal such as ubiquitin-like domain and calmodulin binding domain, which promise BAG proteins to participate in different biological functions. (3) BAG proteins involve in many biological processes including plant response to stress such as temperature, salinity and pathogen infection, and programmed cell death. This article expounds reported researches of functions of BAG proteins in stress response of plant, which may be helpful in enhancing stress tolerance and then improving the study of molecular breeding in crops.
