Research Progress on the Effect of Endoplasmic Reticulum Stress on Skeletal Muscle Cells
LIU Ying1,2, SHI Jian-Kai1, GUO Xiao-Rong2, LIN Xiao3,*, ZHOU Rong2,*
1 School of Life Science and Technology, Inner Mongolia University of Science & Technology, Baotou 014010, China; 2 Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China; 3 Nanning Zhuangbo Biotechnology Co., Ltd., Nanning 530000, China
Abstract：Skeletal muscle has very important roles in both human body and livestock, related to physical function and meat production of livestock. External stimulation or the internal environment changes could make the endoplasmic reticulum (ER) to start a series of protective mechanisms, that is, ER stress. ER stress response has a two-way effect. Proper ER stress can alleviate the cell's inadaptability to living conditions through autophagy, unfolded protein reaction and other behaviors, but the continuous stress of ER caused by adverse factors will affect the normal function of ER and lead to apoptosis. This paper mainly reviewed the researches about the effects of ER stress on lipid metabolism, autophagy, apoptosis, differentiation and other physiological processes and mechanisms of skeletal muscle cells, aiming to provide a theoretical basis for studying the effect of ER stress on skeletal muscle cells.
刘颖, 石建凯, 郭肖蓉, 林晓, 周荣. 内质网应激对骨骼肌细胞影响的研究进展[J]. 农业生物技术学报, 2024, 32(5): 1169-1177.
LIU Ying, SHI Jian-Kai, GUO Xiao-Rong, LIN Xiao, ZHOU Rong. Research Progress on the Effect of Endoplasmic Reticulum Stress on Skeletal Muscle Cells. 农业生物技术学报, 2024, 32(5): 1169-1177.
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