Research Progress on Degradation of Fluoroquinolones by Environmental Microorganisms
SHEN Shu-Qing1,3, LIANG Yi3, MA Jia-Wei4, SUN Yong-Xue3,*, WANG Mei1,2,*
1 College of Animal Science and Technology • College of Veterinary Medicine, Zhejiang A & F University, Hangzhou 311300, China; 2 Zhejiang Key Laboratory of Applied Technology of Green Ecological and Healthy Breeding of Livestock and Poultry, Hangzhou 311300, China; 3 College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China; 4 College of Tea Science and Tea Culture, Zhejiang A&F University, Hangzhou 311300, China
Abstract：Fluoroquinolones (FQs) are one of the most commonly used antibiotics for human medicine and animal breeding. Due to their large dosage, FQs are widely retained in the environment, posing potential threat to human and animal health. Microbial degradation is an ideal way to eliminate FQs in the environment at this stage, which has the characteristics of high efficiency, green and low cost. At present, the research on microbial degradation of FQs mainly focuses on the screening of degradable microorganisms and the identification of degradation products. This paper reviewed the functional characteristics of FQs degradation of bacteria, fungi, microalgae and microorganisms, and summarized the common degradation pathways and key enzymes. This review provides a theoretical basis for alleviating the environmental residue problem of FQs.
神舒晴, 梁仪, 马嘉伟, 孙永学, 王美. 环境微生物降解氟喹诺酮类药物的研究进展[J]. 农业生物技术学报, 2024, 32(6): 1440-1451.
SHEN Shu-Qing, LIANG Yi, MA Jia-Wei, SUN Yong-Xue, WANG Mei. Research Progress on Degradation of Fluoroquinolones by Environmental Microorganisms. 农业生物技术学报, 2024, 32(6): 1440-1451.
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