Contact Us Add to Favorite
 
NianQi Search Adv Search
33
农业生物技术学报  2019, Vol. 27 Issue (12): 2258-2264    DOI: 10.3969/j.issn.1674-7968.2019.12.017
Reviews and Progress Current Issue | Archive | Adv Search |
MEN1/Menin Regulates the Pathogenesis of Non-Alcoholic Fatty Liver Disease
LI Ran-Ran1,*, XU Zhong-Jin1,*, WANG Sheng-Xuan1, YAN Chuan2, SI Bo2, ZHANG Le-Tian1, ZHANG Xuan1, LIU Ting-Jun1, SHI Ke-Rong1,**
1 College of Animal Science and Technology, Shandong Agricultural University/Shandong Key Laboratory of Animal Bioengineering and Disease Prevention, Tai'an 271018, China;
2 Shandong Xianghe Dairy Co., Ltd., Zaozhuang 277412, China
Download: PDF (1295 KB)   HTML (1 KB) 
Export: BibTeX | EndNote (RIS)      
Abstract  Nonalcoholic fatty liver disease (NAFLD) is a clinical pathological syndrome characterized by hepatic steatosis and lipid storage. It is caused by fatty acid synthesis, oxidation, transport, insulin resistance, oxidative stress, gluconeogenesis and other aspects. It was found that the protein menin encoded by the tumor suppressor gene MEN1 can be widely involved in pathways that regulating the liver metabolism. MEN1/menin was an important regulator of liver metabolism and assumed to be closely associated with the pathogenesis of fatty liver disease. This article generally elucidate the research progress of menin in regulating the lipid metabolism, glucose metabolism, insulin resistance and also inflammation.
Key wordsMEN1/menin      Non-alcoholic fatty liver disease (NAFLD)      Liver     
Received: 15 June 2019     
ZTFLH:  S805  
Corresponding Authors: * krshi@sdau.edu.cn   
About author:: *Authors who contribute equally
Service
E-mail this article
Add to my bookshelf
Add to citation manager
E-mail Alert
RSS
Articles by authors
LI Ran-Ran
XU Zhong-Jin
WANG Sheng-Xuan
YAN Chuan
SI Bo
ZHANG Le-Tian
ZHANG Xuan
LIU Ting-Jun
SHI Ke-Rong
Cite this article:   
LI Ran-Ran,XU Zhong-Jin,WANG Sheng-Xuan, et al. MEN1/Menin Regulates the Pathogenesis of Non-Alcoholic Fatty Liver Disease[J]. 农业生物技术学报, 2019, 27(12): 2258-2264.
URL:  
http://journal05.magtech.org.cn/Jwk_ny/EN/10.3969/j.issn.1674-7968.2019.12.017     OR     http://journal05.magtech.org.cn/Jwk_ny/EN/Y2019/V27/I12/2258
Copyright © Editorial Board of 农业生物技术学报
Supported by:Beijing Magtech