Abstract：The aim of the study was to investigate that characterization and antibiotic resistance of Escherichia coli isolated from bovine mastitis in some areas of China for raising therapeutic effect and decreasing drug residues. Milk samples of clinical and subclinical bovine mastitis were collected from seven provinces in China and a total of 95 E. coli isolates were further identified by microbiological tests. Following, serotype, pathogenicity and antibiotic resistance of 95 strains were also studied. The results showed that for the 95 E. coli strains, 54 isolates were identified as 37 serogroups, 2 isolates were self-clumpinged and 39 isolates could not be serotyped, 093 and 09 serotypes were the most common serogroups. Obviously pathological changes were observed in internal organs of dissected experiment mouse(Mus musculus). Among the 95 strains, the rate of drug fast to 8 out of 16 antibacterial drugs exceeded 50%, and a same strain could resisted 14 kinds of antibacterial drugs at most and 2 kinds of antibacterial drugs at least. E. coli strains which were resistant above 6 antibacterial drugs occupied 51.58%. So we concluded that serotypes of E. coli isolates from bovine mastitis were complicate in China, and E. coli isolates had produced different level resistance to many kinds of antibacterial drugs and presented serious multiple antibiotic resistance. This research provides a theoretical basis to further prepare bovine mastitis vaccine and treat bovine mastitis clinically
徐继英1,刘俊林2,李先波2,霍生东2,杨志强. 我国部分地区奶牛乳房炎源大肠杆菌生物学特性及耐药性分析[J]. , 2012, 20(9): 1035-1041.
, , , ,. Characterization and Antibiotic Resistance of Ninety-five Strains of Escherichia coli Isolated from Bovine with Mastitis in Some Regions of China. , 2012, 20(9): 1035-1041.
