Research Progress of Selection Signatures Analysis in Functional Gene Identification of Goat (Capra hircus) and Sheep (Ovis aries)
LIU Wen-Xuan1, LIU Qian-Wei2, CHEN Chong1, WANG Wan-Ting1, LUO Jun1, LI Cong1,*
1 Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China; 2 State Key Laboratory of Crop Stress Biology for Arid Areas, College of Horticulture, Northwest A&F University, Yangling 712100, China
Abstract：Goat (Capra hircus) and sheep (Ovis aries) are main domestic animals raised by human beings. Goat and sheep can be divided into four categories including milk, meat, fleece and both according to its economic use. A clear understanding of the genetic evolution and selection progress of population can be provided through exploring the characteristics of selection signatures among different population. Moreover, the genetic progress can be accelerated and the breeding process can be shortened by applying positive selection. The functional genes detected by the selection signature analyses can be further verified as the causal genes, so as to realize molecular design breeding and the improvement of important economic traits. In this review, the differences and application scopes of five commonly used selection signature detection methods are summarized, and the research progress of functional genes determined using selection signature analyses for important economic traits in goat and sheep are also summarized. This study lays a theoretical foundation for further analysis of the molecular mechanism of functional genes regulating the formation of important economic traits in goat and sheep, and provides genetic sources and molecular materials for population genetic improvement or new varieties (lines) cultivation through molecular design breeding.
刘文轩, 刘倩薇, 陈冲, 王琬婷, 罗军, 李聪. 选择信号分析在羊功能基因挖掘中的研究进展[J]. 农业生物技术学报, 2021, 29(12): 2436-2448.
LIU Wen-Xuan, LIU Qian-Wei, CHEN Chong, WANG Wan-Ting, LUO Jun, LI Cong. Research Progress of Selection Signatures Analysis in Functional Gene Identification of Goat (Capra hircus) and Sheep (Ovis aries). 农业生物技术学报, 2021, 29(12): 2436-2448.
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