Abstract：Albendazole which is a broad-spectrum antiparasitic drugs, plays an important role in aquaculture. But that is overused and inpoured into water directly can has bad effects on human health through the food chains. In order to isolate an albendazole-degrading bacterium, a strain named ZS-1 which could use albendazole as the sole carbon source was isolated from albendazole-contaminated samples. Strain ZS-1 was finally identified as Rhodococcus sp. based on its morphological, physiological,biochemical tests and 16S rRNA gene sequence analysis(GenBank accession: No. KC763472). Degrading characteristics of strain ZS-1 to albendazole showed that ZS-1 could effectively degrade 100 mg/L albendazole in mineral salts media(MM) with albendazole as the sole carbon. Strain ZS-1 could degrade more than 90.6% of 50 mg/L albendazole within 3 d. The best pH and temperature for the albendazole degradation by strain ZS-1 were 7.0 and 30℃, respectively. The ion Cu2+ had obvious inhibition on the degradation of albendazole by strain ZS-1. Our research provide theoretical basis to bioremediation technology of albendazole pollution.
