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| Synthesis and Regulation Research Progress of Chicoric Acid, the Active Ingredient of Echinacea purpurea |
| WANG Zi-Hang1, YU Jian-Bin1, BAI Mei1,2, WU Hong1,2, LIANG Xiang-Xiu1,2,*, YANG Qiao1,* |
1 College of Life Sciences, South China Agricultural University, Guangzhou 510642, China;
2 Lingnan Modern Agriculture Science and Technology Laboratory, Guangzhou 510642, China |
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Abstract Echinacea purpurea is a widely used medicinal plant worldwide with significant economic value,known for its effects in enhancing immunity, antibacterial, and anti-inflammatory properties. The active ingredient chicoric acid is a crucial substance for exerting the medicinal effects of E. purpurea and serves as a key indicator for evaluating the quality of medicinal herbs. The production of active ingredients is not only regulated by its own genetic factors but is also significantly influenced by environmental factors such as light, temperature, and microorganisms in the synthesis and accumulation of active components in E. purpurea. This article mainly elucidated the efficacy of E. purpurea and its active ingredients, further discussed the synthetic pathways of the main active ingredient chicoric acid, summarized the regulatory mechanisms of the genetic characteristics and various environmental factors on the synthesis of chicoric acid, and finally provided an application outlook on the current status of enhance the accumulation of its active ingredients. This review provides new directions for the rational development of E. purpurea resources and is of great importance for improving the quality and clinical efficacy of medicinal plants.
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Received: 06 May 2024
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Corresponding Authors:
* liangxiangxiu@scau.edu.cn; 13025202833@163.com
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