Abstract As a mitochondria-targeted antioxidant, mitoquinone mesylate (MitoQ) has been proved to relieve oxidative stress damage of mitochondria, target mitochondria to resist apoptosis, and maintain body health. Existing research has proven that MitoQ plays an important role in cell damage, organ damage repair and the treatment of various diseases. This paper reviews the biological functions of MitoQ such as antioxidant, resistance to cell inflammation and apoptosis, and its mitochondrial targeting, and systematically summarizes the research progress of MitoQ in the treatment of neurodegenerative diseases, cardiovascular injury, metabolic organ injury, and diabetes. This review provides reference for the use of MitoQ in cell biology and clinical disease treatment.
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