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农业生物技术学报  2024, Vol. 32 Issue (6): 1432-1439    DOI: 10.3969/j.issn.1674-7968.2024.06.018
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Research Progress on Mitochondrial Targeted Antioxidant MitoQ
TAN Ning1, LI Ba-Lun1, Aili·AIERKEN1, ZHAO Xian-Jun1,2, HUA Jin-Lian1,*
1 College of Veterinary Medicine/Shaanxi Centre of Stem Cells Engineering & Technology, Northwest A&F University, Yangling 712100, China;
2 BaiOuPai (Tianjin) Biotechnology Co., Ltd., Tianjin 300350, China
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Abstract  As a mitochondria-targeted antioxidant, mitoquinone mesylate (MitoQ) has been proved to relieve oxidative stress damage of mitochondria, target mitochondria to resist apoptosis, and maintain body health. Existing research has proven that MitoQ plays an important role in cell damage, organ damage repair and the treatment of various diseases. This paper reviews the biological functions of MitoQ such as antioxidant, resistance to cell inflammation and apoptosis, and its mitochondrial targeting, and systematically summarizes the research progress of MitoQ in the treatment of neurodegenerative diseases, cardiovascular injury, metabolic organ injury, and diabetes. This review provides reference for the use of MitoQ in cell biology and clinical disease treatment.
Key wordsMitoquinone mesylate (MitoQ)      Mitochondrion      Anti oxidation      Treatment     
Received: 12 July 2023     
ZTFLH:  R310.11  
Corresponding Authors: * jinlianhua@nwsuaf.edu.cn   
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TAN Ning
LI Ba-Lun
Aili·
AIERKEN
ZHAO Xian-Jun
HUA Jin-Lian
Cite this article:   
TAN Ning,LI Ba-Lun,Aili·, et al. Research Progress on Mitochondrial Targeted Antioxidant MitoQ[J]. 农业生物技术学报, 2024, 32(6): 1432-1439.
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https://journal05.magtech.org.cn/Jwk_ny/EN/10.3969/j.issn.1674-7968.2024.06.018     OR     https://journal05.magtech.org.cn/Jwk_ny/EN/Y2024/V32/I6/1432
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