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| Research Progress on the Biological Function of lncRNA and Its Role in Regulating Residual Feed Intake in Cattle (Bos taurus) |
| MING Wen-Xuan1, ZHAO Zhi-Yan1,2, KANG Xiao-Long1,* |
1 School of Animal Science and Technology, Ningxia University, Yinchuan 750021, China;
2 Yinchuan City Animal Husbandry Technology Extension Service Center, Yinchuan 750000, China |
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Abstract Long non-coding RNA (lncRNA) is an important epigenetic regulator affecting gene expression and cell function, and its expression pattern is tissue-specific. The biological roles of lncRNA have been widely verified in many diseases and biological phenotypes. Feed intake is one of the main factors affecting the economic benefits of livestock. A large number of studies have focused on the effects of nutrition and immune factors on feed intake of livestock, but its genetic analysis and functional research are still slow. In order to explore the biological role of lncRNA in the regulation of feeding behavior and residual feed intake (RFI) in cattle (Bos taurus), the molecular characteristics and main regulatory functions of lncRNA were summarized in this paper. In addition, the biological roles of lncRNA in regulating RFI variation were summarized from important tissues (hypothalamic-pituitary-adrenal cortex axis, liver, skeletal muscle, and brain-gut axis) that affected the phenotype changes of feed intake in cattle. This review provides a basis for subsequent studies to reveal the phenotypic regulation of RFI by lncRNA from a cellular function perspective, and provides reference for efficient production and breed improvement of cattle.
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Received: 03 October 2022
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Corresponding Authors:
*kangxl9527@126.com
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