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| Research Progress of Mitosis and Meiosis in Mammalian Spermatogenesis |
| LI Yun-Xiang, LI Na, HUA Jin-Lian* |
| College of Veterinary Medicine, Northwest A&F University /Stem Cell Engineering Technology Research Center of Shaanxi Province, Yangling 712100, China |
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Abstract The fate of SSC is divided into two kinds in mammalian spermatogenesis, one is self-renewal through mitosis, and the other is differentiation into sperm through meiosis. The balance and orderly transition between SSC's mitosis and meiosis is the key to spermatogenesis in male animals. The review focuses on the key regulatory and influencing factors of SSC's mitosis and meiosis, and key point is the regulation of retinoic acid, methylation of mRNA, and hormones during mitosis to meiosis , it would help us to understand the reproductive mechanism of male mammals, and provide references for the treatment of male infertility or the breeding of excellent sires.
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Received: 29 April 2021
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Corresponding Authors:
*jinlianhua@nwsuaf.edu.cn
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