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| Research Progress on Value Characterization and Uncertainty Evaluation of Reference Materials for Genetically Modified Organisms |
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Abstract Genetically modified organisms detection reference materials(GMOs detection RMs) used in genetically modified organisms (GMOs) detection are essential for GMOs safety supervision, qualitative and quantitative detection. To date, only a few institutions, such as EU Joint Research Centre (Institute for Reference Materials and Measurements, IRMM) and American Oil Chemists' Society (AOCS), have developed certified reference material (CRM) for GMOs testing. In China, research and development of GMOs detection RM are still at the initial stage. Based on the price of CRMs on GMOs testing is very expensive, and the available of CRMs for GMOs can not meet requirements in China, the funding agency in China supported a research project named "Study on RMs for GMOs detection", which aims to develop CRMs for GMOs detection used in Chinese GMOs safety supervision requirements. This paper presented overview on production process and value characterization pattern of current existing RMs based on matrix, genomic DNA and plasmid DNAs. We also addressed the problems in development of RMs of GMOs detection in this paper. This review can provide a useful reference for production of Chinese RMs of GMOs detection, and theoretical basis for value characterization and uncertainty evaluation of RMs.
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Received: 19 June 2013
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