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| Effect of oleic acid on triglycerides (TG) accumulation and mRNA level of tumor necrosis factor α and peroxisome proliferator-activated receptor α in Goose Primary Hepatocytes |
| , ,Chun-Chun Han, ,Ji-Wen Wang, , |
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Abstract In this study, the effect of oleic oil on cytoactive, triglycerides (TG) accumulation, lipids drop and mRNA expression of tumor necrosis factor α（TNFα） and peroxisome proliferator-activated receptor α（PPARα） was measured in primary goose hepatocytes. Results were as follows: 1.5 mmol/L oleic oil had an inhibiting effect on the cell viability; 1.5 mmol/L oleic oil could induce the goose hepatocytic steatosis and the increase of TG content and lipids drop. 0.5，1.0 and 1.5 mmol/L oleic oil all could increase the mRNA level of PPARα; 0.5 and 1.0 mmol/L oleic oil could increase the mRNA level of TNFα, but 1.5 mmol/Loleic oil had no evident effect, demonstrating that the expression of PPARα and TNFα in mRNA level is important for the balance of lipid metabolism in goose hepatocyte.
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Received: 15 February 2009
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Corresponding Authors:
Ji-Wen Wang
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DU Fei, YI Zhi-Xin, YU Hai-Ying, ZHANG Yan, LI Hui-Min, YANG Li, WANG Yu-Zeng, JIANG Dong-Mei, KANG Bo. Effect of Spermine on Expression of Key Genes Related to Polyamine Metabolism and Polyamine Contents in the Duodenum of Female Geese (Anser cygnoides)[J]. 农业生物技术学报, 2019, 27(8): 1445-1451. |
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