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| Inbreeding Line Culture of Wuzhishan Mini-pig and the Innovation in Nurturing Inbred for Chinese Genetic Resources |
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Abstract Experimental animals are important research content of the research conditions. In past more than 20 years, the Wuzhishan mini-pig(Sus scrofa)(WZSP) inbred line has been carried out by Institute of Animal Science, Chinese Academy of Agricultural Sciences, with inbreeding heddle measure. Up to now, inbreeding F22 of pig's herd have been already obtained which has been applied on human medicine industry. Recently, the whole-genomesequencing of the inbred's WZSP was performed which would be inbred for medical experiments. Compared with human(Homo sapiens), macaque(Macaque mulatta) and rat(Rattus norvegicus), the genome of the inbred pig represented the high homozygosity and specific molecular genetic characteristics. In addition, results from the genome sequencing not only reveal reliability of the innovation in nurturing inbred for Chinese genetic resources, also imply that the inbred line pig is an ideal model in human medical research. The cultivation of Chinese miniature pigs has important practical and historical significance
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Received: 14 May 2012
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