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Abstract To get the epitope site of NDV-HN protein which may be identified with mAb 1E5, monoclonal antibody of NDV-HN protein was used to screen the phage display random 7-peptides. The positive clonies were identified by indirect ELISA and competitive ELISA. 4 groups of 7-peptides sequence were got These sequences were located at the residue 388~395 aa of NDV-HN protein.The mutual sequence L * * * PNT is the framework structure. This epitope site is different with former reports, It may be another useful epitope site of NDV-HN protein.
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Received: 12 November 2007
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Corresponding Authors:
Yan-Shun CUI
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