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Abstract Natural biological control agents such as insecticides that exhibit high efficacy, low toxicity, superior selectivity and environmental friendliness, have maintained an important role in integrated pest management of agriculture. This paper provided an overview of recent promising insecticides from natural sources. They were avermectins, spinosyns, meibemucins, and ivermectin. The researches on their efficacies, biochemical properties, mechanism of actions, as well as recent advances in the molecular genetics of the producing microorganisms at home and abroad would be discussed here.
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