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Abstract Analysis of a radiation hybrid panel indicated that porcine TLR4 gene is closely linked to the marker SW1957 (15 cR, LOD score 15.16) which is located on porcine chromosome 1 q2.9-q2.13. Using RT-PCR analysis, porcine TLR4 transcripts were detected in testicle, grey matter, skeletal muscle, white matter, kidney, heart, small intestine, thymus, lymph node, spleen, lung and liver, and the hightest lever expression in lung. These study will facilitate the understanding of porcine TLR4 as a disease resistance/susceptibility candidate gene.
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Received: 21 April 2006
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