Research Progress of Guanine Nucleotide Binding Protein q Polypeptide on Regulation of Mammalian Reproduction
WANG Wei, HE Xiao-Yun*, CHU Ming-Xing*
Key Laboratory of Animal Genetics, Breeding and Reproduction of Ministry of Agriculture and Rural Affairs, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China
Abstract The guanine nucleotide-binding protein q polypeptide (GNAQ) is a member of the α subunit encoding of the q-class G protein and is vital in cell signaling. Studies have shown that GNAQ plays an important role in multiple reproductive-related tissues involved in mammalian reproductive regulation. The present review is concerned with the discovery and mechanism of action of GNAQ, the research progress of GNAQ in mammalian hypothalamic hormone secretion, uterine function, ovarian physiology, male testicular development, and spermatogenesis. This review provides a reference for further exploring the mechanism of GNAQ in mammalian reproduction.
WANG Wei,HE Xiao-Yun,CHU Ming-Xing. Research Progress of Guanine Nucleotide Binding Protein q Polypeptide on Regulation of Mammalian Reproduction[J]. 农业生物技术学报, 2023, 31(3): 643-649.
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